Urea is an natural and organic substance that is probably more known for its role within a fertilizer made use of in agriculture. Urea takes on an important part in your bodies metabolism and is a vital method by which the body eliminates unnecessary nitrogen. It is manufactured within the liver from an ammonia compound via the breakdown of amino acids as being the major result of protein metabolism. It is comprised of two amine chemicals that are bound with each other by a carbonyl chemical group. Back in 1928 the chemist, Friedrich Wöhler proved for the first time that the organic compound may be crafted from inorganic chemical substances when he was able to construct urea from its inorganic components in the research laboratory. The manufactured version of urea is regularly used as a topical cream or external medicine employed to care for an array of skin problems. It’s become so essential because of this that urea is currently listed by the WHO on the List of Essential Medicines which it advocates that most nations be able to access. In skin which is dried out, many experts have shown that there is a considerable loss of urea in your skin, therefore hence the need to use the urea lotions. These kind of skin complaints include simple skin conditions like dried-out skin or the more severe skin disorders including psoriasis, eczema along with ichthyosis. These kinds of ointments are often times made use of by podiatric physicians following the removal of cracked skin surrounding the heels.
These urea lotions have different impacts on different skin complaints determined by their content level in the cream. At levels near 40% the urea can reduce the cellular matrix in the nail plate so can be used to take care of nail dystrophy disorders by dissolving an area of the toenail. This could be useful for disorders like tinea infections on the toe nails. At amounts under that, whilst still being above 20% the urea lotion is known as a keratolytic which means it can cause a breakdown of proteins in your skin, so the dry skin might slough off, especially with the damaged dried-out skin surrounding the heel of the foot. At concentrations of less than about 20% the urea cream acts as a humectant which suggests it can help your skin hold on to moisture and lower water loss and make the skin soft in addition to flexible. Urea comes with a extra benefit because it also has anti itching actions meaning that it may help with those dryer skin complaints that happen to be also itching. There are not really any adverse effects by using these urea products on the epidermis with the exception of an infrequent local aggravation that almost usually clears up when you cease using the urea product. In contrast to a great deal of other medicines, there aren’t any known interactions between urea and some other medicines that may be used. Urea shouldn’t be used if there is a recognized allergy to urea or any of the other substances that are utilized when making the cream. There are practically 100’s of various manufacturers of urea creams including the Walker’s Urea Foot Cream from Australia as well as Glycolix’s Glyco-Urea KP Therapy in the US. At all times steer clear of exposure to your eyes with the urea cream and rinse the hands right after making use of it.
The thyroid gland is in our neck and plays a significant role in regulating a lot of metabolic functions in the body.
One of the main effects on the foot is the thyroid hormone is reduced is that the skin can be more dry, which can be an issues at increasing the problem with cracked heels. The nails are also more likely to becomes detached more easily if they become damaged (onycholysis). Raynauds disease of the skin which is a reaction of the blood vessels to cold is also more common.
One effect is the reflexes are sluggish at returning to normal after being hit with the reflex hammer. This means that when you tap the Achilles tendon and get a reflex, then things are slower to return to normal if there is a a hypothyroidism. This is called Woltman’s Sign of Hypothyroidism, but can also be due to a few other things besides hypothyroidism.
With the use of thyroid hormone replacement as a treatment, most of these impacts on the foot tend to be reversed.
Menopause is by definition the last natural menstrual period and on average happens at an age of 51 years, but it commonly ranges from 45-55yrs. There are many physiological and psychological changes that accompany that. Some of those changes can increase the risk of the development of pain in the foot. This was confirmed in a study of 106 Spanish women that were aged 45-55 years and used a tool called the Foot Health Status Questionnaire and demonstrated a statistical difference in the amount of foot pain between menopausal and non-menopausal women.
Many of the changes that affect the foot are due to the declining estrogen levels that occur during menopause leading to an increased risk of musculoskeletal injury with bone and muscle wasting. The tendons become stiffer and are more prone to injury. All of that can lead to an increased problem with balance and an increased risk for falls. Osteoporosis is more common in post-menopausal women and this increases the risk for stress fracture and fractures in the foot. There is also a significant increase in weight gain following menopause and this will lead to increased loads on foot, increasing the risk for a whole range of foot and ankle problems.
Menopause, per se, does not cause foot pain. What does happen during and after menopause is that a number of the physiological changes that occur increase the risk for the development of a range of both common and uncommon foot problems.
The toe nails in the feet have a great deal of different conditions that may affect them and become uncomfortable. The toe nails get confronted with a lot of pressure and also weight from sneakers and everyday living. The toe nails get bumped around a great deal and also get objects dropped upon them frequently. It’s no surprise that we now have a great number of problems that podiatry practitioners see in their clients with issues of the toenails.
A ingrown toe nail is among the most well-known painful problem with the toes. This takes place if a edge of the toe nail penetrates the skin and establishes an inflammation. This is often in most cases as a result of bent shape to the nail plate as well as a poor toenail trimming technique that leaves a sharp edge. A competent podiatric physician could easily remove that problematic piece of nail plate and allow almost instant pain relief for this. Having said that, the problem can are inclined to be recurrent, therefore a minor surgery to get rid of the edge of the nail plate is highly recommended.
Most likely one of the most prevalent reasons for symptoms around the nails is a problem which is technically named onychophosis. This is when there’s a lot of pressure down the sides of the toe nail that can causes a callus to develop in the nail plate sulcus. This callus or onychophosis becomes so thick that it will become uncomfortable. This is regularly erroneously identified as an ingrown toenail. This type of condition needs the specialist competencies of a podiatrist to meticulously take away the callus from the nail sulcus as well as file the nail plate out of the painful area. Long term if the onychophosis happens to be an ongoing challenge a minor operative technique to eliminate the side of the nail plate can be performed.
Trauma to a toenail plate by, for example, repeated banging with the toe towards the end of the shoe or the one off trauma of, for example, dropping a weighty thing on the foot may lead to a deformed nail plate that grows in a deformed way. The technical period with this is onychogryphosis. Once the nails commences to grow like this, it cannot be resolved. The only way to manage this is to regularly reduce the toenail, probably by a foot doctor or even to have the nail completely removed by minor surgery.
An additional prevalent problem with the nails is a fungal infection or onychomycosis then may cause the nail to take on a whitish or yellowish colour which may fall apart and be deformed. The specific level of distortion of the nail and what color it looks will depend on the exact fungi that infects the toe nail. However for the foot fungi love the dark and moisture and that’s the exact setting that you’ve got in the foot when it’s in footwear. This inhospitable ecosystem helps make the therapy frustrating. Typically, the treatment entails routine reduction of the nail plate as well as the use of a topical agent so that they can hinder the growth of the infection. Other available choices include laser treatment or oral medications. Treatments will last many months and quite a few do often reoccur.